Andropause, sometimes referred to as male menopause, may have a mythic status due to many men’s “don’t ask – don’t tell” unwillingness to acknowledge the condition.  According to the World Health Organization (WHO), “male androgens progressively decline with age.”  This male hormone deficiency – andropause – or “male menopause” really exists.


Between the ages of 40 and 55, men can experience a condition similar to menopause due to a decline in male hormone (androgens) levels, primarily testosterone.  Body changes occur gradually and may be accompanied by symptoms similar to those of menopause.  Symptoms of male hormone deficiency or imbalance include:

  • Accelerated aging of the heart

  • Diminished cognitive function

  • Changes in attitudes and moods

  • Decreased physical agility

  • Depression

  • Erectile dysfunction

  • Fatigue

  • Lack of sex drive

  • Decline in sexual function

  • Loss of competitive edge

  • Loss of energy

  • Rapidly falling level of fitness

  • Increased abdominal fat and shrinkage of muscle mass

  • Stiffness and pain in the muscles and joints


Although andropause may demonstrate a low level of total testosterone, it is better indicated by a deficiency of free testosterone – the form of testosterone that is most bio-available to the body.  Triggers for andropause symptoms that add to the normal effects of aging seem to include:

  • Excess alcohol use

  • Inactivity and lack of exercise

  • Infections

  • Obesity

  • Stress

  • Vasectomy

Hormonal imbalances can also be caused by too much testosterone, free testosterone, estrogen or progesterone. These forms of male hormone imbalances are correctable by establishing baselines with the proper blood tests and using available drugs and nutritional supplements. 

Erectile Dysfunction Solutions

Erectile dysfunction (ED) sometimes called ‘impotence,” is the repeated inability to achieve and maintain an erection of sufficient rigidity for satisfactory sexual intercourse.


First-line therapy for ED is the use of oral drugs called phosphodiesterase (PDE) inhibitors. These drugs do not create immediate erections but require sexual stimulation to attain an erection.  However, oral formulations may not work for approximately 30% of the patients taking them. Patients not responding may be offered second-line therapy.
Second-line therapy for ED is the use of Intracavernous Injection (ICI) therapy.  Medications are injected in the corpora cavernosa, the erectile cylinders of the penis.  ICI therapy is an effective treatment with high success rates of 85%.  Injection therapy can be given as a single agent (monotherapy) or multi-agent mixture as Bi-mix, Tri-mix and Super Tri-mix.
Medications used are:

  • Prostaglandin (E1) – used to relax smooth muscles

  • Papaverine – used to relax smooth muscles

  • Phentolamine – causes blood vessels to expand, increasing blood flow to the penis


Formulations and strengths for Erectile Dysfunction therapies:

  • Single Agent

    • Prostaglandin E1 (PGE-1)

  • Bi-Mix 

    • Papaverine and Phentolamine

    • Phentolamine and Prostaglandin

    • Papaverine and Phentolamine

  • Tri-Mix & Super Tri-Mix

    • Papaverine, Phentolamine and Prostaglandin

Erectile Dysfunction Links:


References: The Management of Erectile Dysfunction: An Update

Men’s Sexual Health & Nutrition

Nutrition can have a lot to do with sexual vitality, which clearly decreases with malnourishment.  A wholesome diet low in saturated fat, moderate in healthy fats, high in fiber and nutrient –dense carbohydrates is a good place to begin.  Any diet (and lifestyle) that maintains good circulation and normal weight and contains high-vitality fresh foods will lead to better sexual function.  A good protein intake is important, but excessive protein may interfere with sexuality.  Likewise, adequate dietary fats and fatty acids are required for normal hormonal function.  Cholesterol is a precursor for several sexual hormones, and if it is too low, this may lead to impaired sexual function and vitality. 


Available OTC Supplements: Complete, DIM, Libido and more

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